What a great article over at Past Horizons about one of the cultural crossroads of antiquity, Dura-Europos! here is a snippet:
Located at the contested borders between the Seleucid, Parthian and Roman Empires—and on the Euphrates River, a major north-south transportation artery—Dura-Europos was home to a multicultural population. Settled by Macedonian veterans around 300 BCE, Parthians captured Dura-Europos late in the second century BCE and made the city into a fortress which flourished as a trading post on the western border of their huge empire.
The religions that coexisted in the city speak of an equally complex cultural environment, with temples to Greek, Roman and numerous Near Eastern gods, as well as dedicated places of worship for Christians and Jews. Abandoned after a Sasanian siege and sack in 256 CE, the site remained virtually unexplored until 1928, when excavations at Dura-Europos were initiated by Yale University.